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1.
Article in English | IMSEAR | ID: sea-156564

ABSTRACT

Gingival recession related to periodontal disease or developmental problems can result in root sensitivity, root caries, and esthetically unacceptable root exposures. In the past, multiple surgical procedures have been proposed to obtain root coverage on exposed buccal root surfaces. There has been great interest in the treatment of gingival recession defects, especially with subepithelial connective‑tissue grafting (SCTG). Recent advances have focused on SCTG by the tunnel technique. This article highlights the esthetic results obtained by adopting a modification of the tunnel technique using a single vertical incision along with autologous SCTG in the management of multiple adjacent Miller Class‑II gingival recessions. A single vertical incision was used along with tunnel preparation for the facile placement of SCTG into the prepared tunnel. After 6 months of follow‑up, the clinical condition was stable with satisfactory root coverage outcome. An excellent esthetical outcome was achieved and the patient was satisfied with the result.


Subject(s)
Connective Tissue/transplantation , /methods , Gingiva/transplantation , /therapy
2.
Article in English | IMSEAR | ID: sea-172356

ABSTRACT

To compare the results of sequential with concurrent chemo radiotherapy in locally advanced squamous cell carcinoma of esophagus in terms of loco regional control, toxicity profile and overall survival,65 patients were enrolled between Jan 2008 and Dec. 2010, of which 37 were male and 28 female. Patients had histologically confirmed squamous cell carcinoma with locally advanced disease with no prior treatment in the form of chemotherapy, radiotherapy or surgery. Patients were divided into two groups and were comparable in terms of patient characteristics. In Group-I, 35 were given sequentially paclitaxel 175mg/ m2, cisplatin 75mg/m2 on day 1 of every 21 days for 3 cycles followed by external beam Radiotherapy followed by 3 more cycles of same chemotherapy. In Group-II, 30 patients were given two cycles of Induction chemotherapy same drugs and dosage as in Group-I and was followed by EBRT concurrent with paclitaxel 30mg/m2 given on day 1 of every week during radiation therapy treatment. The overall objective response rate at the end of treatment was superior 93.33% in Group-II as compared to 74.28% in Group-I. Thrombocytopenia was 73.33% and 17.14% in Group-II and Group-I respectively. Similarly, mucosites was higher 56.66% in Group-II as compared to 22.85% in Group-I. At 2 years of follow up, there was no statistically significant difference seen in overall and disease free survival.

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